post pathology i final exam.
[Legg-Calve-Perthes disease] aseptic necrosis of the femoral head in small dogs. vascular-mediated.
[Canine Panosteitis] diaphyseal enostosis — “medullary fibrosis”
BLASTO LOVES BONE.
Hepatozoon on bone; spares the distal limb.
Lead poisoning (in young’n): osteoclast fail; “lead line”, increased metaphyseal density
Osteoflurosis (only herbivores exposed): soft black teeth! ddx bovine congenital porphyria; blacklight
Hypervitaminosis A (cat eats too much liver): dying chondrocytes form enthesophye, fused joints
Hypervitaminosis D (Solanum, Cestrum, Trisetum; rodenticide): metaphyseal spongy bone sclerotizes.
Veratrum californicum (day 14): cyclops lamb
Hypovitaminosis D, or hypophosphate: soft bones (unmineralized osteoid is resists osteoclast-ism)
HyperPTH: Osteodystrophia fibrosa; increased osteoclast-ism, replaced by fibrosis… rubberbones
Gout: deposition of urates in membranes (poultry, reptiles, humans)
1. Articular gout: Excess protein diet; uric acid deposition in synovial capsules
2. Visceral gout: kidney failure; kidney, heart, etc.
Hypovitaminosis C: hallmarks are capillary hemorrhage & lack of bone deposition (Rickets + bloody)
LORDOSIS: booty sticks out
KYPHOSIS: the opposite
if there is no twisting or lateral deviation, it’s one of those two.
Osteochondritis dissecans (dyschondroplasia; growing large breed dogs, horses): focal area of articular cartilage fails to mineralize. Ischemia plays a big role. Increasing body weight cracks open the cartilage.